Articaine Injection: The Modern Standard in Dental Anesthesia

When it comes to making dental procedures comfortable, few innovations have had the same impact as articaine.

Originally introduced for clinical use in Europe in 1976 and in UK in 1998, articaine has become a leading local anaesthetic in almost every country into which it has been introduced.

• Germany: 96.8% of injectables used in dentistry (1).
• USA: 32.4% of injectables used in dentistry (2).
• UK: 2nd favorite local anesthetic used (2).

What Makes Articaine Injection Special?

Articaine stands out as the only local anesthetic specifically designed for dentistry. Its molecular structure is unique combining features of both amide and ester compounds. This allows it to be broken down not just in the liver (like most amides), but also in the bloodstream by plasma esterases, leading to faster metabolism and reduced toxicity (3).

Efficacy of Articaine in Dental Anesthesia:

• Articaine LA onset takes between 1.5-1.8 minutes for a maxillary infiltration and 1.5-3.6 minutes for mandibular block anaesthesia (4).
• Articaine pulpal anaesthesia lasts between 30-120 minutes, a duration longer than lidocaine, mepivacaine and prilocaine (4).
• Articaine soft tissue anaesthesia lasts approximately 2.25 hours for maxillary infiltrations and 4 hours for mandibular blocks (4).

Why choosing Septanest (Articaine)?

Septodont offers articaine-based local anesthetic formulations under the brand name Septanest. Septanest contains articaine hydrochloride with epinephrine and is widely used in dental practice for its rapid onset, reliable anesthesia, and favorable safety profile.

(1) Source: GFK data 2009

(2) Source: SDM data 2009

(3) Source: Updates in articaine use in dentistry DOI:10.55302/MSP21442-3065l

(4) ResearchOnline@JCU: Articaine in dentistry: safety, efficacy, practitioner perception and evidence-based practice